People > Dr. Largus (Lars) Angenent
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CV
Assistant Professor, Dept. of Energy,
Environmental & Chemical Engineering
Part of the Environmental
Studies Program
Part of the Division of Biology and Biomedical
Sciences
Research Interests:
The Angenent Lab members
incorporate molecular biology techniques, such as PCR assays and hybridization
assays, to solve environmental engineering problems. We are working
on the interface between biology and engineering. The research
can be grouped in three areas: bioprocessing, bioaerosols, and bioindicators.
In the area of bioprocessing our goal is to optimize anaerobic fermentation
processes to grow microorganisms that can convert wastes into bioenergy,
such as biogas (methane), bioelectricity, and biochemicals. We
convert wastewater to electricity by bacteria in microbial fuel cells
and have developed a novel reactor configuration that is promising for
full-scale electricity production. However, further improvement
in power output is necessary, and thus we are pursuing research with
pure cultures that can help us unravel the metabolic mechanisms of electron
transport from bacteria to the electrodes in a microbial fuel cell.
To do this, we will use functional and comparative genomics and metabolomics.
In the research area of bioaerosols, we characterize unknown bacteria
and viruses in indoor air with 16S rRNA gene sequencing technologies
and with DNA chips, respectively. We have also tested a novel
air purifier to remove viruses from air by employing conventional plaque
and qPCR methods. Work on the removal and inactivation of airborne
viral particles is of importance to human health. Airborne viruses
can be present due to "natural" causes or after a deliberate
release in an act of bioterrorism.
Finally, we use bacteriophages and bacteria as bioindicators of pollution.